Acoustic biosensors for ultrasound imaging of enzyme activity
نویسندگان
چکیده
منابع مشابه
Acoustic biosensors
Resonant and acoustic wave devices have been researched for several decades for application in the gravimetric sensing of a variety of biological and chemical analytes. These devices operate by coupling the measurand (e.g. analyte adsorption) as a modulation in the physical properties of the acoustic wave (e.g. resonant frequency, acoustic velocity, dissipation) that can then be correlated with...
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The biosensor field has grown enormously since the first demonstration of the biosensor concept by Leland C. Clark Jr. in 1962. Today’s biosensor market is dominated by glucose biosensors, mass-produced enzyme-electrodes for the rapid self-diagnosis of blood glucose levels by diabetes sufferers. Here we take a historical look at the inception, growth, and development of the enzyme biosensor fie...
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Acoustic wave devices coated with a biolayer represent one biosensor approach for the detection of medically relevant biomolecules. In a typical application, the acoustic wave device is connected in an oscillator circuit, and the frequency shift f resulting from a biomolecular event is recorded. In this paper, we discuss our recent work in this field, which has included the use of Rayleigh wave...
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ژورنال
عنوان ژورنال: Nature Chemical Biology
سال: 2020
ISSN: 1552-4450,1552-4469
DOI: 10.1038/s41589-020-0591-0